Matthew 12:46-50. “While He yet talked to the people, behold, His mother and His brethren stood without, desiring to speak with Him. Then one said unto Him, Behold, Thy mother and Thy brethren stand without, desiring to speak with Thee. But He answered and said unto him that told him, Who is My mother? and who are My brethren? And He stretched forth His hand toward His disciples, and said, Behold, my mother and my brethren! For whosoever shall do the will of My Father which is in heaven, the same is My brother, and sister, and mother.”
Here is a passage that refers to Jesus’ brothers, sisters, and mother in every-day terms. They did not share the same Father, of course, but they were all born of Mary. His four brothers were James, Joses, Simon, and Judas. His sisters, as far as I know, are not named in the scriptures. You will hear again of His family in Matt. 13:55-56, and Mark 6:3.
In the Mark 6:3, we learn that His family had come, apparently, to try to take Him out of the place He was in, fearing that He had lost His mind. It would seem that his own family were not yet believers, and He refused at that time to see them. Their disbelief created a broken relationship, and Jesus spoke of a new relationship based upon obedience to the will of His Father in heaven.
This passage is extremely sad to me. The rejection of Jesus by His own people was now complete, and He moves inexorably toward Calvary. Even His own family, even Mary who knew better, were worried that He had simply become delusional.